Apr 212010
 

The University of Alberta Discovers that Dichloroacetate (DCA) as a possible Cancer Treatment

DCA is an odorless, colorless, inexpensive, relatively non-toxic, small molecule. And researchers at the University of Alberta believe it may soon be used as an effective treatment for many forms of cancer.

Video News Link –  DCA Possible Cure for Cancer (Video) Discussing Dr. Evangelos Michelakis research.

Since this announcement many cancer patients have started this treatment.


The drug Companies have no interest as DCA is a natural substance, they cannot obtain Patents. The possible $100 million cost of clinical trials & testing, approval costs would be lost to other entities.

Fortunately Government Agencies, Universities, Donations etc have got the ball rolling , testing has started.

Michelakis’ research is currently funded by the CIHR, the Canada Foundation for Innovation, the Canada Research Chairs program, and the Alberta Heritage Foundation for Medical Research.

“This preliminary research is encouraging and offers hope to thousands of Canadians and all others around the world who are afflicted by cancer, as it accelerates our understanding of and action around targeted cancer treatments,” said Dr. Philip Branton, Scientific Director of the CIHR Institute of Cancer

Dr. Evangelos Michelakis, a professor at the U of A Department of Medicine, has shown that dichloroacetate (DCA) causes regression in several cancers, including lung, breast, and brain tumors.

Until recently, researchers believed that cancer-affected mitochondria are permanently damaged and that this damage is the result, not the cause, of the cancer. But Michelakis, a cardiologist, questioned this belief and began testing DCA, which activates a critical mitochondrial enzyme, as a way to “revive” cancer-affected mitochondria.

The results astounded him.

Michelakis and his colleagues found that DCA normalized the mitochondrial function in many cancers, showing that their function was actively suppressed by the cancer but was not permanently damaged by it.

More importantly, they found that the normalization of mitochondrial function resulted in a significant decrease in tumor growth both in test tubes and in animal models. Also, they noted that DCA, unlike most currently used chemotherapies, did not have any effects on normal, non-cancerous tissues.

“I think DCA can be selective for cancer because it attacks a fundamental process in cancer development that is unique to cancer cells,” Michelakis said. “One of the really exciting things about this compound is that it might be able to treat many different forms of cancer”.

Another encouraging thing about DCA is that, being so small, it is easily absorbed in the body, and, after oral intake, it can reach areas in the body that other drugs cannot, making it possible to treat brain cancers, for example.

Also, because DCA has been used in both healthy people and sick patients with mitochondrial diseases, researchers already know that it is a relatively non-toxic molecule that can be immediately tested patients with cancer.

“The results are intriguing because they point to the critical role that mitochondria play: they impart a unique trait to cancer cells that can be exploited for cancer therapy”

Dario Alteri Director University of Massachusetts Cancer Center

Patients are currently receiving DCA treatment from Doctors & Medical Centers.

Many Web sites such as The DCA Site – Updating You on DCA and Cancer are providing updates, information & a Chat room for discussion. Information covering many different Cancer types where patients have used DCA.

You can also search the web for more information “DCA cancer”

The Official University of Alberta DCA Website http://www.dca.med.ualberta.ca/Home/index.cfm

Hope this information is helpful

Regards John

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